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Experts generally advise avoiding CBD products in the period immediately before and after surgery. This caution is due to the limited scientific research available on how CBD might interact with anesthesia, medications, or the healing process.
A few small studies have looked at cannabis or cannabinoid-based treatments for appetite and weight loss in individuals living with HIV/AIDS. However, these trials involved very small groups, often lacked strong controls, and may contain bias. At this time, the evidence supporting cannabinoids for this purpose remains limited.
Store the bottle upright at room temperature. Do not freeze or refrigerate. Once opened, the product should be used within 12 months. Dispose of any remaining liquid after that time.
CBD and THC share structural similarities with the endocannabinoids naturally produced by the human body. Because of this, they can interact with cannabinoid receptors that influence mood, communication between neurons, and other bodily processes.
Beginning in the 1970s, federal drug policies led to widespread arrests for cannabis possession and use, shaping decades of legal and social consequences.
The amount of THC in cannabis varies depending on the method of preparation. Concentrated extracts can reach THC levels above 50%, which may increase the risk of dependence or problematic use.
The FDA has issued advisories urging people not to use vaping products containing THC, as these have been linked to many of the reported cases of severe lung injury associated with vaping.
THC and THCA may sound nearly identical—and differ by only a single letter—but they behave very differently in the body. THCA is non-intoxicating until it’s heated, while THC is responsible for the plant’s psychoactive effects.
Researchers are also examining whether THC may offer support for conditions involving chronic pain, including fibromyalgia, though more rigorous trials are needed.
In some studies, cannabinoids performed similarly to placebos, and side effects were reported more often by those taking cannabis-based products.
How long THC remains in your system depends partly on the form used. Edibles, for instance, take longer to metabolize, meaning their effects—and their detectability—may last longer than inhaled methods.
Small, legally compliant amounts of THC in full-spectrum CBD products are unlikely to cause intoxicating effects. Some researchers believe these trace levels may enhance how CBD functions, a concept known as the “entourage effect.”
Edibles can produce strong, long-lasting effects, though they also take the longest to kick in compared with smoking or vaporizing.
Observational studies involving people with PTSD—who decided independently whether or not to use cannabis—have not produced clear conclusions about its helpfulness or risk. Results remain mixed and more controlled research is needed.